This week, Dr. Aundrea Loftley, an Associate Professor of Medicine and endocrinologist at the Medical University of South Carolina (MUSC), discussed the condition of prediabetes and the potential for reversal through lifestyle changes. Bobbi Conner, hosting the segment for South Carolina Public Radio, highlighted that approximately 84 million adults in the U.S. are estimated to have prediabetes, with many remaining unaware of their condition.
Understanding Prediabetes
Dr. Loftley explained that prediabetes occurs when blood sugar levels are elevated but not high enough to be classified as type 2 diabetes. This condition serves as a crucial warning sign, indicating that the body is struggling to manage and utilize glucose effectively.
The doctor pointed out that there are no definitive symptoms associated with prediabetes, which can lead to undiagnosed cases. Diagnosis typically involves noninvasive testing methods such as measuring fasting blood glucose levels, checking hemoglobin A1C levels, or conducting an oral glucose tolerance test. Regular annual check-ups, especially for individuals over 40 or those with risk factors, often include these tests.
Addressing how to manage prediabetes, Dr. Loftley emphasized that the condition is reversible with targeted lifestyle adjustments. Key interventions include regular exercise, adoption of a healthy and balanced diet, and modest weight loss—about 5% of body weight—can significantly improve health outcomes.
Additionally, Dr. Loftley referred to findings from the Diabetes Prevention Program, which demonstrated that such lifestyle changes can reduce the risk of developing type 2 diabetes by 58% compared to those who did not receive any treatment. The most significant risk reduction was observed in adults over the age of 60.
Dr. Loftley’s insights underscore the importance of proactive health management and the role of lifestyle modifications in addressing prediabetes, ultimately preventing the progression to type 2 diabetes.
Why It Matters
With a substantial portion of the U.S. adult population potentially living with prediabetes, awareness and early intervention through lifestyle changes are vital. Effective management of prediabetes can lead to better health outcomes and reduce the incidence of type 2 diabetes, highlighting the importance of regular health screenings and education on nutrition and exercise.


